Studies on the antiviral and cytotoxic activity of Schiff bases derived from 1,2-bis-(o- and p-aminophenoxy) ethane and salicylaldehyde

Bulut H., Karatepe M., Temel H., Sekerci M., Koparir M.

ASIAN JOURNAL OF CHEMISTRY, vol.17, no.4, pp.2793-2796, 2005 (SCI-Expanded) identifier identifier

  • Publication Type: Article / Article
  • Volume: 17 Issue: 4
  • Publication Date: 2005
  • Journal Name: ASIAN JOURNAL OF CHEMISTRY
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.2793-2796
  • Keywords: Schiff base, cytotoxicity, salicylaldehyde, aminophenoxy, antiviral activity, COPPER(II) COMPLEXES, TOSYLATE
  • Yozgat Bozok University Affiliated: Yes

Abstract

A new synthesized derivative of substituted salicylaldehyde Schiff bases of aminophenoxy ethane were selected as new biological agents in the present study. The results indicate that none of the tested compounds was found to be an antiviral agent for DNA (bovine herpesvirus 1; BHV-1) and RNA (parainfluenza-3 viruses; PI-3) viruses used in this study but they possess highly cytotoxic effects.