We carried out a prospective analysis of 86 patients with brucellosis, and 26 (30%) cases were diagnosed as brucellar spondylitis. Two patients had cervical involvement, two thoracic: and 21 lumbosacral as seen in MRI. Four patients had epidural abscess and two had paravertebral abscess. All patients received combined antibiotic therapy for 4 to 12 months. Those with cervical involvement underwent surgical treatment because of medullar compression. Neither death nor severe sequelae were observed.