Preparation and characterization of novel pyrrol-3-ones attached to alpha/beta-amino acids, esters and amides

Sacmaci M., Ungoren Ş. H., Akcamur Y.

AMINO ACIDS, vol.31, no.4, pp.397-401, 2006 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 31 Issue: 4
  • Publication Date: 2006
  • Doi Number: 10.1007/s00726-006-0340-z
  • Journal Name: AMINO ACIDS
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.397-401
  • Yozgat Bozok University Affiliated: Yes


Various alpha/beta amino acid derivatives 5 were attached to compounds 3 to yield 2,3-dihydro-1H-pyrrol-3-ones amino acids derivatives 6. This rare heterocyclic amino acid skeleton including the pyrrolo[1,2-b][1,3]oxazol moiety was also successfully prepared in the esteric form. The structure of the new compounds was characterized by spectroscopic methods.