Akademik Veri Yönetim Sistemi
Afyon Kocatepe Üniversitesi Fen ve Mühendislik Bilimleri Dergisi, cilt.25, sa.2025 , ss.1291-1300, 2025 (TRDizin)
Zinc oxide nanoparticles (ZnO-NPs) were synthesized through a green synthesis method using the extract of Thymbra spicata L. in this study. The T. spicata plant is well known for its pleasant aroma and numerous beneficial effects. The phytochemicals present in this plant act as reducing agents during the synthesis. The characterization of the synthesized ZnO-NPs was performed using XRD analysis, EDX, and STEM imaging. The XRD analysis revealed peaks at 32.81⁰, 35.43⁰, 37.42⁰, 44.51⁰, 55.62⁰, 63.86⁰, 65.42⁰, 68.92⁰, 70.13⁰, 73.52⁰, and 76.77⁰, which are attributed to ZnO-NPs. STEM image analysis showed that the ZnO-NPs were predominantly spherical in shape with an average size of 38 nm. Additionally, with EDX analysis, Zn changes to 36.3% and O changes to 23.8%. The biological activities of the ZnO-NPs synthesized through green synthesis, including antibacterial, antibiofilm, and anticancer properties, were investigated in this study. The ZnO-NPs exhibited antibacterial activity against all tested bacterial strains, with a minimum inhibitory concentration (MIC) of 16 µg/mL determined against S. gordonii NCTC 7870. Furthermore, antibiofilm activity was observed at a very low concentration of 8.55 µg/mL against P. aeruginosa AGME ATCC 27853.