Investigation of Diagnostic Proteins by 2D Electrophoresis in Major Depression Model Induced by Forced Swim Test in Rats


Duman T., Akyuz E., Bulut H., KOÇYİĞİT A., Tulek A., Karatas E., ...More

PROTEIN AND PEPTIDE LETTERS, vol.28, no.2, pp.195-204, 2021 (Journal Indexed in SCI) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 28 Issue: 2
  • Publication Date: 2021
  • Doi Number: 10.2174/0929866527999200729183729
  • Title of Journal : PROTEIN AND PEPTIDE LETTERS
  • Page Numbers: pp.195-204

Abstract

Background: Aside from its pervasiveness, whereby it affects as much as 20% of the world's population, depression continues to be one of the most crucial psychiatric problems due to the loss of power it causes by disrupting daily life functioning, containing economic consequences, and having a high suicidal tendency. Major depression (MD) is a systemic and multifactorial disorder involving complex interactions between genetic predisposition and disturbances of various molecular pathways.