Eco-friendly biogenic silver nanoparticles: synthesis, characterization and biological applications

KORKMAZ N., Ceylan Y., İmamoğlu R., Kısa D., Şen F., KARADAĞ A.

International Journal of Environmental Science and Technology, 2024 (SCI-Expanded) identifier

  • Yayın Türü: Makale / Tam Makale
  • Basım Tarihi: 2024
  • Doi Numarası: 10.1007/s13762-024-05860-w
  • Dergi Adı: International Journal of Environmental Science and Technology
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus, Agricultural & Environmental Science Database, Aqualine, Aquatic Science & Fisheries Abstracts (ASFA), Biotechnology Research Abstracts, CAB Abstracts, Compendex, Environment Index, Geobase, INSPEC, Pollution Abstracts, Veterinary Science Database
  • Anahtar Kelimeler: Biological applications, Bioreduction, Ficus carica, Green synthesis, Silver nanoparticles
  • Yozgat Bozok Üniversitesi Adresli: Evet

Özet

Recent developments in nanotechnology and nanoscience in all phases of human life have radically altered the diagnosis, treatment, and prevention of numerous diseases. Silver nanoparticles (Ag-NPs) have been among the most dynamic, and Several metallic nanoparticles developed for biological uses include some beautiful nanomaterials. Ag-NPs have played a pivotal role in nanotechnology and nanoscience, mostly nanomedicine. In this work, Ficus carica leaf extract was utilized to create silver nanoparticles using a straightforward procedure. This study explored the reduction of silver ions by F. carica leaf extract in the solution. UV–Vis spectroscopy, XRD analysis, and STEM characterize prepared biogenic Ag-NPs. Afterward, antibacterial and antibiofilm properties were investigated. The images obtained from STEM analysis surveyed that the NP sizes ranged from 11 to 20 nm. Ag-NPs demonstrated antibacterial and antibiofilm activities against all tested Gram-positive and Gram-negative bacteria strains. It has been indicated that Ag-NPs have inhibitory potency against collagenase activity. Ag-NPs exhibited anticancer activity in the HeLa cell line, and the IC50 value was calculated as 8.403 μg/mL. In this study, it has been shown that the synthesis method is environmentally friendly, fast, safe, and easy to use.