Aim: Lower urinary tract symptoms (LUTS) secondary to benign prostatic hyperplasia (BPH) are prevalent and interfere with the quality of life (QoL) of older men. According to observational, 22.6% of LUTS/BPH patients reported anxiety or depression. The aim of our study was to investigate the potential influences of anxiety and QoL to LUTS/BPH. Material and Method: We examined consecutive 42 patients admitted to our outpatient clinic with LUTS at Bor State Hospital. We examined and recorded maximum urinary flow rate (Qmax) and International Prostate Symptom Score (IPSS) also Hamilton anxiety rating scale for anxiety and IPSS QoL were utilized in the study. Patients according to IPSS were divided into two groups as moderate (group 1, IPSS <= 19) and severe (group 2, IPSS > 19) LUTS. Patients according to Qmax were divided into two groups as moderate (group 3, Qmax > 9) and severe (group 4, Qmax <= 9) LUTS. Results: The mean Hamilton anxiety rating scale score of group 1 and 2 were 15.4 +/- 3.3 and 21.4 +/- 4.5, respectively (P=0.03); of group 3 and 4 were 13.5 +/- 2.8 and 17.9 +/- 3.5, respectively (P=0.04). The mean QoL score of group 1 and 2 were 3.2 +/- 0.6 and 4.2 +/- 0.9, respectively (P=0.02); of group 3 and 4 were 3 +/- 0.5 and 3.7 +/- 0.6, respectively (P=0.02). Discussion: We found relationship between clinical status, anxiety and QoL in patients with BPH. These psychiatric parameters may help identify individuals to benefit from treatment interventions in daily routine practice.