Neurobrucellosis in an endemic area of brucellosis


Bodur H., Erbay A. , Akinci E., Colpan A., Cevik M.

SCANDINAVIAN JOURNAL OF INFECTIOUS DISEASES, vol.35, no.2, pp.94-97, 2003 (Journal Indexed in SCI) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 35 Issue: 2
  • Publication Date: 2003
  • Doi Number: 10.1080/0036554021000027000
  • Title of Journal : SCANDINAVIAN JOURNAL OF INFECTIOUS DISEASES
  • Page Numbers: pp.94-97

Abstract

Central nervous system involvement occurs less than 5% of patients with brucellosis. A prospective analysis of 73 patients with brucellosis identified 13 (17.8%) neurobrucellosis cases from February 2001 to May 2002. 10 patients had chronic meningitis and 3 acute meningitis. Two patients had only psychiatric disorders. Cranial nerve involvement was observed in 3 patients (6th, 7th and 8th nerves). Three patients had positive blood cultures and 3 others had positive cerebrospinal fluid (CSF) cultures. 12 patients had positive agglutination titres in CSF. All patients received antibiotic therapy with ceftriaxone, rifampicin and doxycycline initially, and after 1 month they were continued with rifampicin and doxycycline up to 4 months. All patients were completely cured. Hearing loss developed in I patient as a sequela.