Spinal cord injury can cause considerable changes in a person's life depending on the functional disability. We aimed to evaluate the psychological status and related factors in patients with spinal cord injury. Subjects included 44 adult persons (29 males; 15 females) who had a SCI (mean age= 34.25 +/- 4.42). Functional status, depression and anxiety were assessed by Functional Independence Measure Beck Depression Inventory, Beck Anxiety Inventory respectively. The mean scores of anxiety and depression were 22.7 +/- 12.9 and 25.6 +/- 9.14, respectively. There was significant negative correlation between anxiety and depression scores with Functional Independence Measure (FIM) scores (r =-0.674, p < 0.001; r =-0.486, p < 0.001). Both anxiety and depression scores were decreased gradually from level A to level D. Anxiety and depression scores were positively correlated with the level of education in patients (r = 0.104, p >0.05; r = 0.202, p> 0.05). There was negative correlation between the ages and anxiety-depression scores (r = -0.249, p > 0.05; r=-0.239, p> 0.05). Clinicians should determine the potential risk factors for psychological problems and support for the necessary treatment in patients with SCI. The influence of pre morbid factors in the development of depression and anxiety must also be acknowledged as a possibility.