Effects of oxaliplatin and 5-fluorouracil on the healing of colon anastomoses

ERSOY P. E., AKBULUT H., Moray G.

SURGERY TODAY, cilt.39, sa.1, ss.38-43, 2009 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 39 Sayı: 1
  • Basım Tarihi: 2009
  • Doi Numarası: 10.1007/s00595-008-3795-6
  • Dergi Adı: SURGERY TODAY
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.38-43
  • Anahtar Kelimeler: Wound healing, Oxaliplatin, 5-Fluorouracil, EARLY POSTOPERATIVE 5-FLUOROURACIL, COLORECTAL-CANCER, ADJUVANT THERAPY, INTERFERON, STRENGTH, ACID
  • Yozgat Bozok Üniversitesi Adresli: Hayır

Özet

Oxaliplatin (OX) and 5-fluorouracil (5-FU) are the most widely used chemotherapeutic agents in the adjuvant treatment of colon cancer. Although the early initiation of adjuvant chemotherapy can improve the outcome of surgery, it carries potentially fatal risks. This experimental study investigates the effects of 5-FU and OX on colon anastomoses.