The objective of this study is to analyse the long-run dynamic relationship of carbon dioxide emissions, real gross domestic product (GDP), the square of real GDP, energy consumption, trade and tourism under an Environmental Kuznets Curve (EKC) model for the Organization for Economic Co-operation and Development (OECD) member countries. Since we find the presence of cross-sectional dependence within the panel time-series data, we apply second-generation unit root tests, cointegration test and causality test which can deal with cross-sectional dependence problems. The cross-sectionally augmented Dickey-Fuller (CADF) and the cross-sectionally augmented Im-Pesaran-Shin (CIPS) unit root tests indicate that the analysed variables become stationary at their first differences. The Lagrange multiplier bootstrap panel cointegration test shows the existence of a long-run relationship between the analysed variables. The dynamic ordinary least squares (DOLS) estimation technique indicates that energy consumption and tourism contribute to the levels of gas emissions, while increases in trade lead to environmental improvements. In addition, the EKC hypothesis cannot be supported as the sign of coefficients on GDP and GDP(2) is negative and positive, respectively. Moreover, the Dumitrescu-Hurlin causality tests exploit a variety of causal relationship between the analysed variables. The OECD countries are suggested to invest in improving energy efficiency, regulate necessary environmental protection policies for tourism sector in specific and promote trading activities through several types of encouragement act.