ARCHIVES OF MEDICAL SCIENCE, vol.18, no.5, pp.1364-1371, 2022 (SCI-Expanded)
Article / Article
ARCHIVES OF MEDICAL SCIENCE
Science Citation Index Expanded (SCI-EXPANDED), Scopus, Academic Search Premier, CAB Abstracts, CINAHL, EMBASE, Veterinary Science Database, Directory of Open Access Journals
cisplatin, ovary, oxidative stress, pycnogenol, rat, uterus, PINE BARK EXTRACT, ANTIOXIDANT ACTIVITY, OXIDATIVE STRESS, RAT MODEL, INFLAMMATION, THIAMINE, ASSAY
Yozgat Bozok University Affiliated:
Introduction: Cisplatin is an antineoplastic agent, which is thought to act on tissues with increased levels of reactive oxygen species and decreased levels of antioxidants. Pycnogenol is a potent antioxidant that is used in medical conditions caused by oxidative stress. The aim of our study is to demonstrate the effects of pycnogenol on cisplatin-induced uterine and ovarian damage in rats.