Thymosin beta-4 overexpression correlates with high-risk groups in gastric gastrointestinal stromal tumors: A retrospective analysis by immunohistochemistry

Sahin S., EKİNCİ Ö., Seckin S., DURSUN A.

PATHOLOGY RESEARCH AND PRACTICE, vol.213, no.9, pp.1139-1143, 2017 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 213 Issue: 9
  • Publication Date: 2017
  • Doi Number: 10.1016/j.prp.2017.07.005
  • Journal Name: PATHOLOGY RESEARCH AND PRACTICE
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.1139-1143
  • Yozgat Bozok University Affiliated: Yes

Abstract

Background: Thymosin beta-4 (T beta 4) is a protein that is linked to a number of important biological actions and recently tumor progression and poor prognosis of some tumors. The aim of this study was to evaluate T beta 4 expression in gastric GISTs and correlate with some clinicopathological characteristics related with prognosis and clinical outcome in order to add further data to the current literature.