The Association of Diastolic Dysfunction and Circadian Variation of Blood Pressure in Prehypertension
Journal of the American Society of Echocardiography, cilt.22, sa.6, ss.726-731, 2009 (SCI-Expanded, Scopus)
- Yayın Türü: Makale / Tam Makale
- Cilt numarası: 22 Sayı: 6
- Basım Tarihi: 2009
- Doi Numarası: 10.1016/j.echo.2009.02.006
- Dergi Adı: Journal of the American Society of Echocardiography
- Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
- Sayfa Sayıları: ss.726-731
- Anahtar Kelimeler: Diastolic dysfunction, Nondipper, Prehypertension
- Yozgat Bozok Üniversitesi Adresli: Evet
Özet
Objective: In this study, we aimed to investigate the relationship between circadian blood pressure variations and left ventricular diastolic functions in patients with prehypertension. Methods: The study population consisted of 48 patients with nondipper prehypertension and 60 patients with dipper prehypertension. Conventional diastolic function parameters, tissue Doppler, and color M-mode flow parameters were obtained during echocardiographic examination. Results: The early diastolic septal myocardial velocity (E' septal) and early diastolic lateral myocardial velocity (E' lateral) were significantly decreased in nondippers (7.0 ± 1.2 cm/s vs 9.2 ± 2.3 cm/s, P < .01 and 11.4 ± 2.4 cm/s vs 10.2 ± 2.4 cm/s, P < .05). Mitral propagation velocity (Vp) was also significantly lower in nondippers than in dippers (48.2 ± 8.3 cm/s vs 61.3 ± 25.2 cm/s, P < .05). The ratio of E/E' septal, E/E' lateral, and E/Vp was significantly different between dippers and nondippers. Conclusion: Diastolic parameters were impaired in nondipper prehypertensive patients. This may indicate diminished diastolic function that may contribute to hypertension in the near future. © 2009 American Society of Echocardiography.