The comprehensive evaluation of latent tuberculosis infection in health care workers and of patients with active tuberculosis using TST, ELISA, and ELISPOT methods

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ŞİMŞEK H., Alpar S. M., Aksu K., Aksu F., Ceyhan I., Cesur S., ...Daha Fazla

TURKISH JOURNAL OF MEDICAL SCIENCES, cilt.40, sa.4, ss.585-591, 2010 (SCI-Expanded) identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 40 Sayı: 4
  • Basım Tarihi: 2010
  • Doi Numarası: 10.3906/sag-0907-85
  • Dergi Adı: TURKISH JOURNAL OF MEDICAL SCIENCES
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus, TR DİZİN (ULAKBİM)
  • Sayfa Sayıları: ss.585-591
  • Anahtar Kelimeler: IFN-gamma tests, QFT-G, T-SPOT.TB test, tuberculin skin test (TST), latent TB, INTERFERON-GAMMA ASSAY, RAPID DETECTION, ENUMERATION, DIAGNOSIS
  • Yozgat Bozok Üniversitesi Adresli: Hayır

Özet

Aim: Until recently, the tuberculin skin test (TST) has been the only assay used for detecting latent tuberculosis infection (LTBI), but two ex-vivo tests, used as alternative methods to TST, based on enumerating the M tuberculosis-specific interferon (IFN)-gamma response are now commercially licensed The aim of this study was to compare the sensitivity and specificity of TST, QuantiFERON Gold (QFT-G), and T-SPOTTB in diagnosing LTBI and active tuberculosis (TB)