29. ulusal türk ortopedi ve travmatoloji kongresi, Antalya, Türkiye, 22 - 27 Ekim 2019, ss.111
Object: This study aimed to determine the amounts of elements in the osteoarthritic knee. Methods: The study was carried out on the surgical waste of 31 patients who underwent total knee arthroplasty with the diagnosis of stage 3 gonarthrosis according to Kellgren and Lawrence classification between 2017 and 2018. We measured the amounts of elements in medial tibial joint surface where macroscopic degeneration is present and in lateral tibial joint surface with low degeneration with Inductively Coupled Plasma Mass Spectrometry (ICP-MS). Materials: In our study, we found the mean elemental amounts in the medial tibial joint surface of 31 patients as 2.52 mgSr/L; 20.12 µgSe/L; 3.83 µg Mn/L; 3298.95 mgCa/L; 1.98 mgZn/L; 0.012 mgCu/L. When we compare these values with the amount of elements in the lateral tibial joint surface with no macroscopical arthrosis, we can see that there were statistically significant differences in all the elements except copper. We also found a decrease in the amount of zinc and an increase in the amount of other elements (except copper) in the surface of the arthritic cartilage. Result: The study also revealed that the element amounts in the arthrotic joint may vary according to the different anatomical location of the same tissue. Except for copper, the average values of the elements in the tibial plateau decrease with age. There is no difference between sexes. Furthermore, the amounts of elements in different anatomical regions of the tissue also vary.