Could edaravone prevent gentamicin ototoxicity? An experimental study
HUMAN & EXPERIMENTAL TOXICOLOGY, vol.36, no.2, pp.123-127, 2017 (SCI-Expanded, Scopus)
- Publication Type: Article / Article
- Volume: 36 Issue: 2
- Publication Date: 2017
- Doi Number: 10.1177/0960327116639360
- Journal Name: HUMAN & EXPERIMENTAL TOXICOLOGY
- Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
- Page Numbers: pp.123-127
- Yozgat Bozok University Affiliated: Yes
Abstract
Objectives: Clinical application of gentamicin may cause nephrotoxicity and ototoxicity. Our study is the first study to investigate the protective effects of edaravone against the gentamicin-induced ototoxicity. We investigated the protective effect of intraperitoneal (i.p.) edaravone application against gentamicin-induced ototoxicity in guinea pigs.