Could edaravone prevent gentamicin ototoxicity? An experimental study

Turan M., Ciger E., Arslanoglu S., Borekci H., Onal K.

HUMAN & EXPERIMENTAL TOXICOLOGY, vol.36, no.2, pp.123-127, 2017 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 36 Issue: 2
  • Publication Date: 2017
  • Doi Number: 10.1177/0960327116639360
  • Journal Name: HUMAN & EXPERIMENTAL TOXICOLOGY
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.123-127
  • Yozgat Bozok University Affiliated: Yes

Abstract

Objectives: Clinical application of gentamicin may cause nephrotoxicity and ototoxicity. Our study is the first study to investigate the protective effects of edaravone against the gentamicin-induced ototoxicity. We investigated the protective effect of intraperitoneal (i.p.) edaravone application against gentamicin-induced ototoxicity in guinea pigs.