Could edaravone prevent gentamicin ototoxicity? An experimental study

Turan M., Ciger E., Arslanoglu S., Borekci H., Onal K.

HUMAN & EXPERIMENTAL TOXICOLOGY, cilt.36, sa.2, ss.123-127, 2017 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 36 Sayı: 2
  • Basım Tarihi: 2017
  • Doi Numarası: 10.1177/0960327116639360
  • Dergi Adı: HUMAN & EXPERIMENTAL TOXICOLOGY
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.123-127
  • Yozgat Bozok Üniversitesi Adresli: Evet

Özet

Objectives: Clinical application of gentamicin may cause nephrotoxicity and ototoxicity. Our study is the first study to investigate the protective effects of edaravone against the gentamicin-induced ototoxicity. We investigated the protective effect of intraperitoneal (i.p.) edaravone application against gentamicin-induced ototoxicity in guinea pigs.