Evaluation of 865 children who underwent magnetic resonance imaging under propofol-midazolam sedation Propofol-midazolam sedasyonu altında magnetik rezonans görüntüleme yapılan 865 çocuk hastanın değerlendirilmesi

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Keskin G., Akin M., Şenayli Y., Saydam S., Özmert S., Kurt D. T., ...More

Medeniyet Medical Journal, vol.32, no.3, pp.141-146, 2017 (Scopus) identifier

  • Publication Type: Article / Article
  • Volume: 32 Issue: 3
  • Publication Date: 2017
  • Doi Number: 10.5222/mmj.2017.141
  • Journal Name: Medeniyet Medical Journal
  • Journal Indexes: Scopus, TR DİZİN (ULAKBİM)
  • Page Numbers: pp.141-146
  • Keywords: Child, Magnetic resonance imaging, Midazolam, Propofol
  • Yozgat Bozok University Affiliated: Yes


© 2017, Logos Medical Publishing. All rights reserved.Implementation of sedatives during magnetic resonance imaging (MRI) in pediatric patients is often preferred. Propofol and midazolam are mostly chosen drugs, and it is suggested that these drugs have synergistic effects. However, studies with large populations in order to observe the possible complications of this combination are very few. In this study we aimed to evaluate the effectiveness, side effects, complications in 865 children undergoing MRI with propofol-midazolam sedation. Anesthesia charts of 865 children sedated for MRI between January 2010 and December 2015 were analyzed retrospectively. Standardized sedation protocol was used. General features, demographic parameters and complications were recorded. Results were compared and discussed in the light of the literature. Median age of the patients was 3.01 years, and 89.2% of the patients were classified in ASA II-III risk groups. While 79.9% of the patients had neurological impairment. Respiratory depression, bradycardia, allergic reactions and hiccup were recorded, and these side effects were seen in 1.9% of the patients. Respiratory depression was the mostly seen complication. In pediatric patients usage of a standard propofol and midazolam regimen is a very effective method with a lower complication rate. Effectiveness was nearly 98%. Allergic reactions and hiccup were very rare. When compared with literature, it seems that rates and types of complications will increase with escalating number of patients. We can also pronounce that ASA risk classification is not a predictive factor to decide whether or not to perform MRI examination under anesthesia.