Disassembly of polymeric nanoparticles with enzyme-triggered polymer unzipping: polyelectrolyte complexesvs.amphiphilic nanoassemblies


Kumar V., Munkhbat O., Secinti H., Thayumanavan S.

CHEMICAL COMMUNICATIONS, vol.56, no.60, pp.8456-8459, 2020 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 56 Issue: 60
  • Publication Date: 2020
  • Doi Number: 10.1039/d0cc03257c
  • Journal Name: CHEMICAL COMMUNICATIONS
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus, Academic Search Premier, Chimica, Communication Abstracts, EMBASE, MEDLINE, DIALNET
  • Page Numbers: pp.8456-8459
  • Yozgat Bozok University Affiliated: No

Abstract

Alkaline phosphatase (ALP) responsive polymers, which can unzip from head to tail are reported. Hydrophilic and hydrophobic modification of the polymer was carried out for the formation of a polyelectrolyte complex and an amphiphilic nanoassembly, respectively, which offered distinct enzyme-triggered disassembly kinetics.