Synthesis and characterization of new thiadiazole derivatives bearing a pyrazole moiety

SAÇMACI M., Arslaner C., ŞAHİN E.

PHOSPHORUS SULFUR AND SILICON AND THE RELATED ELEMENTS, vol.192, no.10, pp.1134-1139, 2017 (SCI-Expanded) identifier identifier


A series of thidiazole derivatives (4, 7) from pyrazole-3-carboxylic acid chloride (2) and pyrazole-3,4-dicarboxylicacid chloride derivatives (6) were synthesized and characterized. The structures of the new compounds were confirmed byelemental analysis, NMR (H-1 and C-13) and IR spectra. The molecular and crystal structure of 4-benzoyl-N-[5-(methylthio)-1,3,4-thiadiazol-2-yl]-1,5-di-phenyl-1H-pyrazole-3carboxamide(4d)was determined by single crystal X-ray diffraction method.