POLISH JOURNAL OF ENVIRONMENTAL STUDIES, vol.21, no.6, pp.1849-1854, 2012 (SCI-Expanded)
In our study, the effect of simultaneous pretreatment with plasma levels of vitamins C and E on the toxicity of CdCl2 in human erythrocytes was evaluated. We aimed to examine how several different doses of CdCl2 or CdCl2, in combination with vitamins, affects lipid peroxidation and the antioxidant defense system in vitro. Levels of malondialdehyde and the activities of antioxidant enzymes changed in CdCl2-treated groups in different concentrations. Vitamin-pretreated erythrocytes showed significant protection aganist the cytotoxic effects induced by low and moderate CdCl2 concentrations on the studied parameters.