The effect of microorganisms on cytokine secretion from bone marrow dendritic cells


FİDAN I., KALKANCI A., Yesilyurt E. , Erdal B., Kustimur S., Imir T.

TURKISH JOURNAL OF MEDICAL SCIENCES, vol.40, no.4, pp.557-563, 2010 (Journal Indexed in SCI) identifier identifier

  • Publication Type: Article / Article
  • Volume: 40 Issue: 4
  • Publication Date: 2010
  • Doi Number: 10.3906/sag-0805-59
  • Title of Journal : TURKISH JOURNAL OF MEDICAL SCIENCES
  • Page Numbers: pp.557-563
  • Keywords: Dendritic cells, microorganisms, cytokines, MONOCYTE-DERIVED MACROPHAGES, CANDIDA-ALBICANS, ANTIINFLAMMATORY CYTOKINES, INTERFERON-GAMMA, BACTERIA, ACTIVATION, RESPONSES, STIMULI, ANTIGEN, BLOOD

Abstract

Aim: Dendritic cells (DCs) are potent antigen-presenting cells crucial for initiation of cell-mediated immune responses to foreign antigens They also contribute to the innate resistance against microbial pathogens. The present study examined the effect of microorganisms such as Escherichia coli (E coli), Serratia marcescens (S marcescens), Methicillin:resistant Staphylococcus aureus (MRSA), coagulase negative staphylococci (CoNS), and Canadida albicans (C albicans) on cytokine secretion in bone marrow-dendritic cells (BM-DCs)