Sacrococcygeal teratoma is the most common congenital tumor in newborns. Sometimes these tumors may have huge sizes and high vascularity. During excision of this teratoma in neonates, hemorrhage can be associated with serious perinatal morbidity and mortality. In this case report, we present anaesthesia management of 4450 g male newborn on postnatal 3rd day who was born by caserean delivery with 15×10 cm sacrococygeal teratoma at gestation of 38 weeks. In this report, the importance of preoperative meticulus preparation and intraoperative close hemodynamic monitorization are emphasized.