In this study, the relationship between psychological-subjective well-being levels, emotional availability to parents, quality of romantic relationships, and social connectedness of pre-service teachers were examined through loneliness. The study group of the research study consists of students who study at Bozok University Faculty of Education, have a romantic relationship, live separately from their families, and whose parents are alive. The total number of participants is 667, 408 of which are females, and 259 are males. In this study, the Psychological Well-Being Scale, the short form of the Oxford Happiness Scale, the UCLA Loneliness Scale, the Parental Emotional Availability Scale, the Perceived Relationship Quality Components Inventory, and the Social Connectedness Scale were used. SPSS 23 and Mplus 7.0 were used to analyze the data. The data obtained were tested by correlation and path analyses. It was determined that emotional availability to parents, romantic relationship quality, and social connectedness predicted subjective and psychological well-being through loneliness.