Are thermogenic proteins and adipokine chemerin affected by monoclonal antibody therapy in asthma?


Bulut T., Yalcin A. D. , ÇELİK B., Genc G. E. , GÖÇMEN A. Y. , GÜMÜŞLÜ S.

EURASIAN JOURNAL OF PULMONOLOGY, vol.21, no.3, pp.161-166, 2019 (Journal Indexed in ESCI) identifier

  • Publication Type: Article / Article
  • Volume: 21 Issue: 3
  • Publication Date: 2019
  • Doi Number: 10.4103/ejop.ejop_60_18
  • Title of Journal : EURASIAN JOURNAL OF PULMONOLOGY
  • Page Numbers: pp.161-166

Abstract

BACKGROUND: Irisin is a thermogenic protein that sources outgoing energy by converting white adipose tissue to brown adipose tissue. Chemerin is originally identified as a chemoattractant protein that mainly mediating the chemotaxis of dendritic cells and natural killer cells (NKCs). The aim of this study is to assess the potential impact of immune modulation-related chemerin and irisin concentrations together with cell surface markers (CSM) in allergic asthmatic patients under omalizumab treatment.