The Motifs from Isocytosine and Fused Isocytosine with Quinazoline: Organocatalytic Cascade Reaction of beta-Ketoamides


ÜNGÖREN Ş. H. , Ozturk M., Degerli E. A.

CHEMISTRYSELECT, vol.6, no.12, pp.2919-2922, 2021 (Journal Indexed in SCI) identifier identifier

  • Publication Type: Article / Article
  • Volume: 6 Issue: 12
  • Publication Date: 2021
  • Doi Number: 10.1002/slct.202100203
  • Title of Journal : CHEMISTRYSELECT
  • Page Numbers: pp.2919-2922

Abstract

A method for the synthesis of isocytosine analogs from beta-ketoamides was investigated. Application of the method to beta-ketoamides including a 2-cyanoaryl group leads to isocytosine fused quinazolines by the organocatalytic Cascade reaction. 20 examples of pyrimidone derivatives were synthesized in different patterns.