Prevalence of hepatitis C virus and hepatitis G virus in patients with non-Hodgkin's lymphoma


Kaya H., Polat M. F. , Erdem F., Gundogdu M.

CLINICAL AND LABORATORY HAEMATOLOGY, vol.24, no.2, pp.107-110, 2002 (Journal Indexed in SCI) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 24 Issue: 2
  • Publication Date: 2002
  • Doi Number: 10.1046/j.1365-2257.2002.00427.x
  • Title of Journal : CLINICAL AND LABORATORY HAEMATOLOGY
  • Page Numbers: pp.107-110
  • Keywords: hepatitis C virus, hepatitis G virus, non-Hodgkin's lymphoma, INFECTION, HCV, ASSOCIATION, HGV, DISEASES

Abstract

Hepatitis C virus (HCV) and hepatitis G virus (HGV) belong to the same family of flaviviridea. A causative role of HCV infection in the pathogenesis of non-Hodgkin's lymphoma (NHL) has been discussed widely. Little is known about the possible association between NHL and HGV discovered recently. In this study, anti-HCV and HGV-RNA prevalence were investigated in a group of 70 patients with NHL. The results were compared to a control group of 70 age- and sex-matched healthy subjects. One patient in each group (1.4%) was found to be anti-HCV-positive; the difference was not statistically significant (P > 0.05). Five subjects in the patient group (7.1%) were positive for HGV-RNA, while a single subject was positive in the control group (1.4%); the difference was not statistically significant (P > 0.05). Odds ratios for anti-HCV and HGV-RNA were 1 and 5.30, respectively. Our findings suggest that neither HCV nor HGV are causative or contributing factors in the aetiopathogenesis of NHL.