Is caffeic acid phenethyl ester more protective than doxycycline in experimental periodontitis?

Yigit U., KIRZIOĞLU F. Y., Uguz A. C., NAZIROĞLU M., Ozmen O.

ARCHIVES OF ORAL BIOLOGY, cilt.81, ss.61-68, 2017 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 81
  • Basım Tarihi: 2017
  • Doi Numarası: 10.1016/j.archoralbio.2017.04.017
  • Dergi Adı: ARCHIVES OF ORAL BIOLOGY
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.61-68
  • Yozgat Bozok Üniversitesi Adresli: Hayır

Özet

Background and objectives: Host modulation therapies (anti-inflammatory drugs, bone-stimulating agents, antiproteinase etc.) target the inhibition or stabilization of tissue breakdown. The aim of the present study was to evaluate the effects of caffeic acid phenethyl ester (CAPE) and/or low dose doxycycline (LDD) administrations on alveolar bone loss (ABL), serum cytokines and gingival apoptosis, as well as the levels of oxidants and antioxidants in rats with ligature-induced periodontitis.