Is caffeic acid phenethyl ester more protective than doxycycline in experimental periodontitis?
ARCHIVES OF ORAL BIOLOGY, vol.81, pp.61-68, 2017 (SCI-Expanded, Scopus)
- Publication Type: Article / Article
- Volume: 81
- Publication Date: 2017
- Doi Number: 10.1016/j.archoralbio.2017.04.017
- Journal Name: ARCHIVES OF ORAL BIOLOGY
- Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
- Page Numbers: pp.61-68
- Yozgat Bozok University Affiliated: No
Abstract
Background and objectives: Host modulation therapies (anti-inflammatory drugs, bone-stimulating agents, antiproteinase etc.) target the inhibition or stabilization of tissue breakdown. The aim of the present study was to evaluate the effects of caffeic acid phenethyl ester (CAPE) and/or low dose doxycycline (LDD) administrations on alveolar bone loss (ABL), serum cytokines and gingival apoptosis, as well as the levels of oxidants and antioxidants in rats with ligature-induced periodontitis.