Two novel cyanido-bridged bimetallic polymeric complexes, [Ni(hydeten)(2)Ag(CN)(2)] [Ag(CN)(2)]center dot H2O (C1) and [Cd-2(hydeten)(2)Ag-4(CN)(8)]center dot H2O (C2) (hydeten: N-(2-hydroxyethyl)ethylenediamine) were synthesized and characterized by elemental, FT-IR, X-ray (C2), thermal and variable temperature magnetic measurement (C1) techniques. Their anticancer, antibacterial and antifungal effects were also investigated. The crystallographic analyses showed that C2 crystallizes in the monoclinic space group P2(1)/c and shows a 3D 6,4 ladder-type polymeric chain in which the Cd-II centers are linked by [Ag(CN)(2)](-) units. The Ag center dot center dot center dot Ag distance exhibits a short value of 3.1365(9) angstrom. It features a rare linear pentameric unit of [Ag(CN)(2)](-) ions assembled via d(10)-d(10) interaction as building blocks. Both complexes exhibited outstanding antibacterial, antifungal and anticancer activities against ten different bacterial strains, two plant pathogenic fungi (Altemaria solani and Rhizoctonia solani) and four tumor cell lines (HT-29, HeLa, C6 and Vero), respectively.