A Fast Regularized Least Squares Method for Retinal Vascular Oxygen Tension Estimation

Gunay G., Yıldırım İ.

World Congress on Engineering (WCE 2013), London, Canada, 3 - 05 July 2013, pp.2244-2246 identifier identifier

  • Publication Type: Conference Paper / Full Text
  • Volume:
  • City: London
  • Country: Canada
  • Page Numbers: pp.2244-2246
  • Yozgat Bozok University Affiliated: Yes


Regularization of least squares estimation method was proposed earlier in order to improve estimation of oxygen tension in retinal vessels and it was shown to be very effective. Optimum points for cost function of the regularized least squares (RLS) estimation were found using iterative methods which do not require considerable computations for small oxygen tension (pO(2)) maps. However, as pO(2) maps get larger, iterative solutions become computationally expensive. In this study, to find optimum points of the RLS cost functions of larger pO(2) images, we propose an accelerated solution derived from closed form solution of the RLS cost function.