Severity Scoring Index for Crimean-Congo Hemorrhagic Fever and the Impact of Ribavirin and Corticosteroids on Fatality

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Dokuzoguz B., Celikbas A. K., Gok Ş., Baykam N., Eroglu M. N., Ergonul O.

CLINICAL INFECTIOUS DISEASES, vol.57, no.9, pp.1270-1274, 2013 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 57 Issue: 9
  • Publication Date: 2013
  • Doi Number: 10.1093/cid/cit527
  • Journal Name: CLINICAL INFECTIOUS DISEASES
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.1270-1274
  • Keywords: Crimean-Congo hemorrhagic fever, severity scoring index, ribavirin, corticosteroids, ORAL RIBAVIRIN, RISK-FACTORS, EFFICACY, THERAPY, TURKEY
  • Yozgat Bozok University Affiliated: Yes

Abstract

Background. Patients infected with Crimean-Congo hemorrhagic fever (CCHF) virus present with a wide clinical spectrum. In observational studies, the effects of therapeutic agents are confounded by severity. We describe use of a clinical severity scoring index (SSI) for CCHF patients and assess the effect of ribavirin and corticosteroid therapy on the case-fatality rate, stratified by SSI.