Scintigraphic evaluation of the osteoblastic activity of rabbit tibial defects after HYAFF11 membrane application


Creative Commons License

Mermerkaya M. U. , Doral M. N. , Karaaslan F., HURİ G., Karacavus S., KAYMAZ B., ...More

JOURNAL OF ORTHOPAEDIC SURGERY AND RESEARCH, vol.11, 2016 (Journal Indexed in SCI) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 11
  • Publication Date: 2016
  • Doi Number: 10.1186/s13018-016-0393-y
  • Title of Journal : JOURNAL OF ORTHOPAEDIC SURGERY AND RESEARCH

Abstract

Background: An unfavorable condition for bone healing is the presence of bone defects. Under such conditions, a material can play a role to cover fractured or defective bone. Technological advances now allow for the use of such material. Hyalonect (R) (Fidia Advanced Biopolymers SLR, Italy), a novel membrane comprising knitted fibers of esterified hyaluronan (HYAFF11) can be used to cover fractured or grafted bone and can also serve as a scaffold to keep osteoprogenitor cells in place. The aim of this study was to compare osteoblastic activity by the use of scintigraphic methods in defective rabbit tibias during early-phase bone healing with or without a hyaluronan-based mesh.