Development of HPLC Methods for Individual Determination of 20 Active Pharmaceutical Ingredients for Ussing-Chamber Studies


KAYNAK M. S. , Akgeyik E. , ATEŞ M., ÇELEBİER M., ŞAHİN S.

CURRENT PHARMACEUTICAL ANALYSIS, vol.13, no.2, pp.145-153, 2017 (Journal Indexed in SCI) identifier identifier

  • Publication Type: Article / Article
  • Volume: 13 Issue: 2
  • Publication Date: 2017
  • Doi Number: 10.2174/1573412912666161018145031
  • Title of Journal : CURRENT PHARMACEUTICAL ANALYSIS
  • Page Numbers: pp.145-153

Abstract

Background: The aim of this study was to develop HPLC methods for individual determination of 20 active pharmaceutical ingredients (amoxicillin sodium, antipyrine, atenolol, caffeine, carbamazepine, cimetidine, enalapril, furosemide, hydrochlorothiazide, ibuprofen, ketoprofen, metoprolol tartrate, methyldopa, naproxen sodium, pindolol, piroxicam, propranolol HCl, ranitidine, theophylline, and verapamil HCl) to be used for determination of their intestinal permeabilities across Ussing-Chamber.