Synthesis and Structural Characterization of Pyrrole Heterocyclic Systems Bearing Amino Acid Units: Novel Pyrrol-3-ones, Pyrrolo[1,2-a][3,1]benzoxazines, and Pyrrolo[2,1-b][1,3]oxazoles
JOURNAL OF HETEROCYCLIC CHEMISTRY, cilt.51, sa.1, ss.212-218, 2014 (SCI-Expanded, Scopus)
- Yayın Türü: Makale / Tam Makale
- Cilt numarası: 51 Sayı: 1
- Basım Tarihi: 2014
- Doi Numarası: 10.1002/jhet.1509
- Dergi Adı: JOURNAL OF HETEROCYCLIC CHEMISTRY
- Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
- Sayfa Sayıları: ss.212-218
- Yozgat Bozok Üniversitesi Adresli: Evet
Özet
Furan-3-one derivatives 1 were converted into 2-hydroxy-pyrrole-3-ones 4 by reacting with various - and -amino acids. In contrast, the reaction of furan-3-ones and 1-aminocyclobutanecarboxylic acid afforded spiro-pyrrolo[2,1-b][1,3]oxazoles 5 via the pyrrole-3-one intermediate under the same reaction conditions. Some of 2-hydroxy-pyrrole-3-ones 3 derived from anthranilic acids were transformed to pyrrolo[1,2-a][3,1]benzoxazines via intramolecular esterification.