Assessment of nitric oxide, advanced oxidation protein products, malondialdehyde, and thiol levels in patients with restless legs syndrome

BAŞKOL G., Korkmaz S., Erdem F., CANİKLİOĞLU A., Kocyigit M., Aksu M.

SLEEP MEDICINE, vol.13, no.4, pp.414-418, 2012 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 13 Issue: 4
  • Publication Date: 2012
  • Doi Number: 10.1016/j.sleep.2011.11.012
  • Journal Name: SLEEP MEDICINE
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.414-418
  • Keywords: Restless legs syndrome, Nitric oxide, Malondialdehyde, Advanced oxidation protein products, LIPID-PEROXIDATION, ENDOTHELIAL DYSFUNCTION, DOPAMINE TRANSPORTER, STRESS, DISEASE, ANTIOXIDANTS, STRIATUM, BIOCHEMISTRY, INFLAMMATION, DIAGNOSIS
  • Yozgat Bozok University Affiliated: Yes

Abstract

Objectives: We aimed to determine the importance of oxidative stress in the pathogenesis of restless legs syndrome (RLS) by quantification of advanced oxidation protein products and total thiol levels (as markers of oxidative protein damage), nitric oxide levels (as an antioxidant and endothelial function), and malondialdehyde levels (as a marker of lipid peroxidation) in patients with RLS.