Assessment of nitric oxide, advanced oxidation protein products, malondialdehyde, and thiol levels in patients with restless legs syndrome


BAŞKOL G., Korkmaz S., Erdem F., CANİKLİOĞLU A., Kocyigit M., Aksu M.

SLEEP MEDICINE, cilt.13, sa.4, ss.414-418, 2012 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 13 Sayı: 4
  • Basım Tarihi: 2012
  • Doi Numarası: 10.1016/j.sleep.2011.11.012
  • Dergi Adı: SLEEP MEDICINE
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.414-418
  • Anahtar Kelimeler: Restless legs syndrome, Nitric oxide, Malondialdehyde, Advanced oxidation protein products, LIPID-PEROXIDATION, ENDOTHELIAL DYSFUNCTION, DOPAMINE TRANSPORTER, STRESS, DISEASE, ANTIOXIDANTS, STRIATUM, BIOCHEMISTRY, INFLAMMATION, DIAGNOSIS
  • Yozgat Bozok Üniversitesi Adresli: Evet

Özet

Objectives: We aimed to determine the importance of oxidative stress in the pathogenesis of restless legs syndrome (RLS) by quantification of advanced oxidation protein products and total thiol levels (as markers of oxidative protein damage), nitric oxide levels (as an antioxidant and endothelial function), and malondialdehyde levels (as a marker of lipid peroxidation) in patients with RLS.