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SAÇMACI H., SABAH ÖZCAN S.
MULTIPLE SCLEROSIS AND RELATED DISORDERS, vol.38, 2020 (SCI-Expanded)
Article / Article
MULTIPLE SCLEROSIS AND RELATED DISORDERS
Science Citation Index Expanded (SCI-EXPANDED), Scopus, EMBASE, MEDLINE
Atypical chemokine receptor 2 (ACKR2), Interleukin-33 (IL-33), Inflammation, Immunopathogenesis, Cytokines, Multiple sclerosis (MS), INTERLEUKIN-33, D6, RESPONSES, NOMENCLATURE, INFLAMMATION
Yozgat Bozok University Affiliated:
Background: : ACKR2 is an atypical chemokine receptor that promotes acute inflammation by acing as a scavenger receptor for inflammatory chemokines in experimental models of some inflammatory disorders, but its function in multiple sclerosis (MS) is unclear. Therefore we aimed to evaluate the mRNA expression of ACKR2 as a scavenger receptor in patients with MS and also the correlation of this expression with certain cytokines that are important for MS pathogenesis.