THE EFFECTS OF MATERNAL HYPOTHYROIDISM ON THE IMMUNOREACTIVITY OF CYTOCHROME P450 AROMATASE IN THE POSTNATAL RAT TESTICLES


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Yildirim A. B. , Ozdamar S., Kaymak E.

ACTA ENDOCRINOLOGICA-BUCHAREST, vol.13, no.1, pp.7-16, 2017 (Journal Indexed in SCI) identifier

  • Publication Type: Article / Article
  • Volume: 13 Issue: 1
  • Publication Date: 2017
  • Doi Number: 10.4183/aeb.2017.7
  • Title of Journal : ACTA ENDOCRINOLOGICA-BUCHAREST
  • Page Numbers: pp.7-16
  • Keywords: testicles, aromatase, hypothyroidism, PCR, THYROID-HORMONE, NEONATAL-HYPOTHYROIDISM, LEYDIG-CELLS, EXPRESSION, IMMUNOLOCALIZATION, TRIIODOTHYRONINE, PROLIFERATION, LOCALIZATION, DISEASE, PLASMA

Abstract

Introduction. Abnormal thyroid function affect spermato-genesis and male infertility. For men, the aromatase deficiency can cause infertility. In this study, the aim is to investigate the effect of maternal hypothyroidism on offspring testicular morphology and cytochrome-P450-aromatase (P450arom) immunoreactivity.