Elevated serum arginase activity levels in patients with breast cancer


Polat M. F., Taysi S., Polat S., Boyuk A., Bakan E.

SURGERY TODAY, cilt.33, sa.9, ss.655-661, 2003 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 33 Sayı: 9
  • Basım Tarihi: 2003
  • Doi Numarası: 10.1007/s00595-002-2563-2
  • Dergi Adı: SURGERY TODAY
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.655-661
  • Anahtar Kelimeler: breast cancer, tumor marker, enzyme, arginase activity, HUMAN COLORECTAL-CANCER, GASTRIC-CANCER, CELL-LINES, CARCINOMA, TISSUES, MARKERS, BLOOD, TUMOR
  • Yozgat Bozok Üniversitesi Adresli: Evet

Özet

Purpose. Recently, the high activity of arginase enzyme has been observed in the sera of malignant neoplasms. In this pathogenic condition, it is said that arginase strongly inhibits lymphocyte proliferation and plays a role in providing ornithine as a substrate for biosynthesis of polyamines, which have been found in various types of cancer. The aim of this study was to examine the arginase activity levels in breast cancer as a marker.