Capsanthin induces death in human prostate cancer cell lines by inducing DNA damage


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Eraslan E. , Erden Y., Oruç S., Bircan B., Gunay S.

EUROBIOTECH JOURNAL, vol.6, no.3, pp.99-104, 2022 (Journal Indexed in ESCI) identifier

  • Publication Type: Article / Article
  • Volume: 6 Issue: 3
  • Publication Date: 2022
  • Doi Number: 10.2478/ebtj-2022-0010
  • Title of Journal : EUROBIOTECH JOURNAL
  • Page Numbers: pp.99-104
  • Keywords: Capsanthin, Prostate cancer, Cell Culture, DNA damage, Cell Viabili, BREAST-CANCER, CAROTENOIDS, PROLIFERATION, LYCOPENE, DIETARY, RISK, MORTALITY

Abstract

There is a relationship between a person's diet and the development and prevention of some cancers. Carotenoids are found as various natural pigments in many fruits and vegetables. Studies on carotenoids and their potential roles in carcinogenesis are increasing in importance day by day. In this study, we aimed to determine the cytotoxic and genotoxic effects of capsanthin, a carotenoid compound, in human prostate cancer cell lines.