Serum Th1, Th2 and Th17 cytokine profiles and alpha-enolase levels in recurrent aphthous stomatitis

Ozyurt K., ÇELİK A., Sayarlioglu M., ÇÖLGEÇEN E., Inci R., Karakas T., ...More

JOURNAL OF ORAL PATHOLOGY & MEDICINE, vol.43, no.9, pp.691-695, 2014 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 43 Issue: 9
  • Publication Date: 2014
  • Doi Number: 10.1111/jop.12182
  • Journal Name: JOURNAL OF ORAL PATHOLOGY & MEDICINE
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.691-695
  • Keywords: alpha-enolase, Behcet's disease, interleukin-17, recurrent aphthous stomatitis, Th17, REGULATORY T-CELLS, BEHCETS-DISEASE, PERIPHERAL-BLOOD, IL-17, EXPRESSION, ANTIBODIES, T(H)17, TARGET
  • Yozgat Bozok University Affiliated: Yes

Abstract

BackgroundAll aspects of aetiopathogenesis of recurrent aphthous stomatitis (RAS) have not been elucidated. RAS and Behcet's disease (BD) have clinical and immunological characteristics in common. Although T17 cytokines and alpha-enolase have been shown to play effective roles in BD and many other autoinflammatory diseases recently, their roles in RAS have not been studied extensively. In the present study, we investigated levels of several Th1, Th2 and Th17 pathways related cytokines and alpha-enolase to elucidate pathogenesis of RAS and to obtain data about possible treatment alternatives for the condition.