Dried yogurt and quinoa attenuate neurodegeneration and cranial bone alterations in protein-deficient rats: a histopathological and radiological study

alan b., KAVAK V., KURT D.

Anatolian Current Medical Journal, cilt.8, sa.3, ss.385-392, 2026 (TRDizin)

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 8 Sayı: 3
  • Basım Tarihi: 2026
  • Doi Numarası: 10.38053/acmj.1887680
  • Dergi Adı: Anatolian Current Medical Journal
  • Derginin Tarandığı İndeksler: TR DİZİN (ULAKBİM)
  • Sayfa Sayıları: ss.385-392
  • Yozgat Bozok Üniversitesi Adresli: Evet

Özet

Aims: This study focuses on experimental studies conducted on rats to explain the effects of malnutrition and poor nutrition, dry yogurt diet, and quinoa diet on skull measurements. Methods: Newborn rat pups were divided as a 2% protein diet, a 12% protein diet, a 24% protein diet, a dry yogurt diet, and a quinoa diet. The diets were isocaloric and were administered from day 22 prenatal, the weaning period, until 90 days of age. Skull measurements were taken from lateral and anterior skull X-rays.Results: In the 22 nd day of the 2% protein diet fed offspring rats, the average brain weight was 1.1550±0.094 and the averagebrain weight was 1.470±0.080 on the 90th day, p=0.001. The average body weight of the 22nd day of the 2% protein diet-fed baby rats was 19.20±3.238 and the average body weight was 95.461±6.233 on the 90 th day. p=0.001. Significant changes in cranial structure were observed in 90-day-old rats fed diets containing 24%, 12%, and 2% protein, as well as dry yogurt and quinoa.Bone measurements were significantly shorter in low-protein diets. Skull length, facial length, nasal bone length, and Orbit length optic canal suture results in the 2% and 24% protein modeling were: 2.66±0.03-4.07±0.1, p<0.0001. 1.74±0.1-2.72±0.0,p<0.0001. 0.82±0.0-1.45±0.1, p<0.0001, and 0.11±0.0-0.13±0.1, p<0.0001, respectively.Conclusion: Dried yogurt and quinoa supplementation significantly enhanced body and brain weights in rat pups compared to 2% and 12% protein diets, particularly reversing the deficits observed in protein-restricted cohorts.