An experimental study on the use of lycopene to prevent infertility due to acute oxidative ovarian damage caused by a single high dose of methotrexate


TÜRKLER C., ONAT T. , Yildirim E., Kaplan S., YAZICI G. N. , MAMMADOV R., ...More

ADVANCES IN CLINICAL AND EXPERIMENTAL MEDICINE, vol.29, no.1, pp.5-11, 2020 (Journal Indexed in SCI) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 29 Issue: 1
  • Publication Date: 2020
  • Doi Number: 10.17219/acem/111809
  • Title of Journal : ADVANCES IN CLINICAL AND EXPERIMENTAL MEDICINE
  • Page Numbers: pp.5-11

Abstract

Background. Methotrexate (MTX) is an antineoplastic agent, which increases the level of reactive oxygen species (ROS) and decreases the level of antioxidants. Lycopene, is a potent antioxidant, which is used because of its protective effect against tissue damage.