Changes in the expression and methylation levels of the MMP-2, MMP-9, TIMP-1, TIMP-2 and VEGF-A genes in children with acute lymphoblastic leukemia
CUKUROVA MEDICAL JOURNAL, vol.46, no.2, pp.825-833, 2021 (Journal Indexed in ESCI)
Article / Article
Title of Journal :
CUKUROVA MEDICAL JOURNAL
Acute lymphoblastic leukemia, MMP, TIMP, VEGF-A, ENDOTHELIAL GROWTH-FACTOR, BONE-MARROW, MATRIX METALLOPROTEINASES, ANGIOGENESIS
Purpose: The aim of this article is to show the expression and methylation levels of matrix metalloproteinases (MMPs), tissue inhibitors of metalloproteinases (TIMPs) and vascular endothelial growth factor (VEGF)genes in patients diagnosed with childhood acute lymphoblastic leukemia (ALL) and their relationship with clinical findings.