A Novel Potentiometric Sensor for Determination of Neurotoxin ss-N-Oxalyl-L-alpha, ss-Diaminopropionic Acid

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Isildak O., Saymaz F., Karadag A., Korkmaz N., ATTAR A.

BIOMED RESEARCH INTERNATIONAL, vol.2014, 2014 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 2014
  • Publication Date: 2014
  • Doi Number: 10.1155/2014/251653
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Yozgat Bozok University Affiliated: No


A novel potentiometric sensor based on ionophore (Cd(NH2CH2CH2OCH2CH2OCH2CH2NH2)Ag-3(CN)(5)) for the determination of beta-N-oxalyl-L-alpha, beta-diaminopropionic acid (ODAP) is developed. The ODAP-selective membrane sensor demonstrates high sensitivity and short response time. The detection limit of the ODAP-selective membrane sensor is about 2 X 10(-6) mol L-1 and the response time is shorter than 6 s. The linear dynamic range of the ODAP-selective membrane sensor is between ODAP concentrations of 1.0 X 10 (2) and 1 X 10 (6) mol L (1). The ODAP-selective membrane sensor exhibits good operational stability for at least one week in dry conditions at 4-6 degrees C. It has a reproducible and stable response during continuous work for at least 10 h with a relative standard deviation of 0.28% (n - 18).