COVID-19 Mortality: Does Age and Gender Really Matter?


Özkan F., Sari S., DEMİREL A.

Anestezi Dergisi, cilt.31, ss.103-112, 2023 (Scopus, TRDizin) identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 31
  • Basım Tarihi: 2023
  • Dergi Adı: Anestezi Dergisi
  • Derginin Tarandığı İndeksler: Scopus, Academic Search Premier, Central & Eastern European Academic Source (CEEAS), EMBASE, TR DİZİN (ULAKBİM)
  • Sayfa Sayıları: ss.103-112
  • Anahtar Kelimeler: Age, COVID-19 mortality, gender, predict
  • Yozgat Bozok Üniversitesi Adresli: Evet

Özet

Background: Identifying the risk factors that increase mortality in Covid-19 patients and taking the necessary precautions can significantly improve the management against this disease. In this study, it was aimed to examine the factors affecting mortality and the ratios of age and gender on mortality in 500 patients diagnosed with Covid-19 in our hospital. Material and Methods: This study was carried out in 500 patients hospitalized in the intensive care unit with the diagnosis of covid-19. The inclusion criteria were to be over 18 years old and diagnosed with covid-19. The patients' age, gender, body mass index, date of admission to the intensive care unit, the length of stay in the intensive care unit, levels of creatinine, CRP, neutrophil-lymphocyte ratio, procalcitonin, D-Dimer, Pt-PTT-INR and fibrinogen in the blood samples taken on the first day in the intensive care unit were recorded and analyzed. Effects on mortality were investigated retrospectively with data from patient records. Result: Of 500 patients included in the study, 34.6% (n=173) survived; 65.4% (n=327) died. Of those who died, 200 were male patients and 18 were under 55 years of age. There was no significant difference in mortality percentages in terms of gender, but mortality was higher in patients over 55 years of age. The length of stay in the intensive care unit, PCT, D-Dimer and PTT values of those who died under the age of 55 were statistically significantly higher than those who survived (p=0.006; p=0.021; p=0.030; p=0.010). The length of stay in the intensive care unit, mechanical ventilation requirement, creatinine, CRP, NEU and PCT values were statistically significantly higher than those who died in the 55 years and older age group (p=0.001; p=0.007; p=0.001; p=0.001; p= 0.010; p=0.001).BMI and lymphocyte levels of male subjects were found to be statistically significantly higher than females(p=0.001). The creatinine, CRP, PCT, PTT and fibrinogen values of women were found to be statistically significantly higher than men (p=0.003; p=0.001; p=0.001; p=0.011; p=0.001). There was no statistically significant difference in mortality status, length of stay in the intensive care unit, mechanical ventilation requirement, neutrophil, D-Dimer, PTand INR values of the participants according to genders (p>0.05). Conclusion: Although the prevalance was higher in men,no gender difference was observed on mortality. Age factor was found to be significantly effective on covid-19.