Evaluation of the corneal endothelium by specular microscopy in patients with chronic obstructive pulmonary disease
CLINICAL RESPIRATORY JOURNAL, cilt.15, sa.10, ss.1056-1062, 2021 (SCI-Expanded, Scopus)
- Yayın Türü: Makale / Tam Makale
- Cilt numarası: 15 Sayı: 10
- Basım Tarihi: 2021
- Doi Numarası: 10.1111/crj.13408
- Dergi Adı: CLINICAL RESPIRATORY JOURNAL
- Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus, Academic Search Premier, EMBASE, MEDLINE
- Sayfa Sayıları: ss.1056-1062
- Anahtar Kelimeler: chronic obstructive pulmonary disease, coefficient of variation, corneal endothelium, specular microscopy, RISK-FACTORS, THICKNESS, SMOKING, CELL, LAYER
- Yozgat Bozok Üniversitesi Adresli: Evet
Özet
Objective The objective of this study is to evaluate the corneal endothelium in patients with chronic obstructive pulmonary disease (COPD) using a specular microscope. Methods The right eyes of 64 patients with a COPD diagnosis and 65 healthy individuals were evaluated. Cell density (CD) (cell/mm(2)), corneal thickness (CT) (mu), hexagonal cell ratio (%), and coefficient of variation (cell area standard deviation/mean cell area, mu m(2)) were analyzed by specular microscopy (SM). Results The CT was significantly reduced in the COPD group compared with the control group (P = 0.021). Moreover, a significant difference was found between the COPD group and the control group in terms of corneal endothelial CD (P = 0.011), hexagonal cell ratio (P = 0.008), and coefficient of variation (P = 0.012). Conclusion The corneal endothelial structure was significantly deteriorated in patients with COPD compared with the control group. SM is a valuable method that could be used in treatment and follow-up of corneal endothelium in patients with COPD.