Low levels of circulating platelet factor 4 (PF4, CXCL4) in subclinically hypothyroid autoimmune thyroiditis

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GÖRAR S., ADEMOĞLU E., ÇARLIOĞLU A., ALİOĞLU B., BEKDEMİR H., SAĞLAM B., ...More

JOURNAL OF ENDOCRINOLOGICAL INVESTIGATION, vol.39, no.2, pp.185-189, 2016 (SCI-Expanded)

• Publication Type: Article / Article
• Volume: 39 Issue: 2
• Publication Date: 2016
• Doi Number: 10.1007/s40618-015-0348-x
• Journal Name: JOURNAL OF ENDOCRINOLOGICAL INVESTIGATION
• Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
• Page Numbers: pp.185-189
• Yozgat Bozok University Affiliated: Yes

Abstract

Purpose Chemokines play an important role in the pathogenesis of autoimmune thyroid diseases. Platelet factor 4 (PF4, CXCL4) released from activated platelets is a chemokine. However, its clinical importance in autoimmune thyroiditis remains unknown. This study is intended to determine circulating levels of PF4 levels in patients with autoimmune thyroiditis (AIT).