Could Lycopene Protect Against Ischemia/Reperfusion Injury in the Uterus?


ONAT T., DOĞANYİĞİT Z., Caltekin M. D. , TÜRKLER C., KAYMAK E., Altindag M. M.

ISTANBUL MEDICAL JOURNAL, vol.22, no.2, pp.155-160, 2021 (Journal Indexed in ESCI) identifier

  • Publication Type: Article / Article
  • Volume: 22 Issue: 2
  • Publication Date: 2021
  • Doi Number: 10.4274/imj.galenos.2021.82698
  • Title of Journal : ISTANBUL MEDICAL JOURNAL
  • Page Numbers: pp.155-160
  • Keywords: Ischemia/reperfusion damage, oxidative stress, organ transplantation, lycopene, NF-KAPPA-B, ISCHEMIA-REPERFUSION INJURY, LIPID-PEROXIDATION, ACTIVATION, TRANSPLANTATION, TRANSCRIPTION, APOPTOSIS, RATS

Abstract

Introduction: Ischernia/reperfusion damage (IRD) is one of the most important factors in the success of organ transplantation. IRD plays a role in both acute and chronic rejection. This study aims to evaluate the effects of lycopene, which is known to be a powerful antioxidant, on experimental uterine IRD.