Purpose This study aimed to determine the association between nurses' perceptions of individualized care and empathic tendencies. Design and Methods This cross-sectional study was conducted with 269 nurses working in Yozgat City Hospital between June 2018 and December 2018. Data were collected with the Personal Information Form, Individualized Care Scale-A-Nurse Version, Empathic Tendencies Scale. For the analysis, descriptive statistics,ttest, analysis of variance, Pearson's correlation, multivariate linear regression analysis were used. Findings Marital status, education level, length of service, clinic worked in, number of patients, and empathic tendency level was determined to be statistically significant predictive factors for nurses' perceptions of individualized care (P < .05). Practice Implications Nurse managers can organize in-service training programs to improve clinical nurses' perceptions of individualized care, empathic tendencies, and skills.