Pharmacophore Modelling and 4D-QSAR Study of Ruthenium(II) Arene Complexes as Anticancer Agents (Inhibitors) by Electron Conformational-Genetic Algorithm Method
CURRENT COMPUTER-AIDED DRUG DESIGN, vol.14, no.1, pp.79-94, 2018 (SCI-Expanded, Scopus)
- Publication Type: Article / Article
- Volume: 14 Issue: 1
- Publication Date: 2018
- Doi Number: 10.2174/1573409913666170529103206
- Journal Name: CURRENT COMPUTER-AIDED DRUG DESIGN
- Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
- Page Numbers: pp.79-94
- Yozgat Bozok University Affiliated: No
Abstract
Objective: The EC-GA method was employed in this study as a 4D-QSAR method, for the identification of the pharmacophore (Pha) of ruthenium(II) arene complex derivatives and quantitative prediction of activity.