Pharmacophore Modelling and 4D-QSAR Study of Ruthenium(II) Arene Complexes as Anticancer Agents (Inhibitors) by Electron Conformational-Genetic Algorithm Method


Yavuz S., Sabanci N., SARIPINAR E.

CURRENT COMPUTER-AIDED DRUG DESIGN, vol.14, no.1, pp.79-94, 2018 (SCI-Expanded) identifier identifier identifier

Abstract

Objective: The EC-GA method was employed in this study as a 4D-QSAR method, for the identification of the pharmacophore (Pha) of ruthenium(II) arene complex derivatives and quantitative prediction of activity.